Unraveling the genetic Code: Pharmacogenomics’ Role in personalized Drug Responses

Review Article

Authors

  • Dev Kumar Ray Student, B-Pharmacy, College of Pharmacy, RIMT University (147301), Gobindgarh, Punjab, India Author
  • Dipendra Kohar Student, B-Pharmacy, College of Pharmacy, RIMT University (147301), Gobindgarh, Punjab, India. Author
  • Rajip Nepal Student, B-Pharmacy, College of Pharmacy, RIMT University (147301), Gobindgarh, Punjab, India Author
  • Prabal Sharma Student, B-Pharmacy, College of Pharmacy, RIMT University (147301), Gobindgarh, Punjab, India. Author
  • Vishal Kajal Assist. Professor, College of Pharmacy, B-Pharmacy, RIMT University (147301), Gobindgarh, Punjab, India Author
  • Yuvraj Singh Student, B-Pharmacy, Lala Birkha Ram College of Pharmacy Golpura Barala District,Panchkula (134118) HR, India Author
  • Jyoti Phogat Research Scholar, MM College of pharmacy, Maharishi Markandeshwar (Deemed to be University), Mullana, Ambala- 133207, Haryana, India Author

Keywords:

Pharmacogenomics, Genetic code, Genetic variation, Personalized medicine, Pharmacogenomic testing, Customized drug therapy

Abstract

The purpose of this review is to shed light on the intricate relationship between an individual's genetic make-up and their response to medicine. As we investigate this complex field, we aim to pinpoint the different ways that genetic variations affect the safety and effectiveness of pharmacological treatments. Knowing How Genetics Affect Drug Reaction, Pharmacogenomics is based on the detection of genetic differences in the transporters, receptors, and enzymes that the body uses to metabolize drugs. These differences greatly increase the inter-individual variability in pharmaceutical metabolism, which results in minute differences in the efficacy and toxicity of medications. This section highlights how important it is to comprehend these. This review delves into the potentially transformative effects of pharmacogenomic testing in the context of personalized medicine. By understanding some patient's genetic code, these tests offer a singular opportunity to customize drug therapy to their genetic profile. This not only improves the efficacy of therapy but also lowers the possibility of negative side effects, which aligns with the principles of customized medicine. As a result, this study successfully navigates the challenging area of pharmacogenomics and highlights how it has a significant impact on changing how we treat patients with medications. Better patient care as well as improved treatment results might result from the discoveries made in this field

Downloads

Download data is not yet available.

Downloads

Published

01-12-2023

How to Cite

Unraveling the genetic Code: Pharmacogenomics’ Role in personalized Drug Responses: Review Article. (2023). Journal of Pharma Insights and Research, 1(2), 015-020. https://jopir.in/index.php/journals/article/view/29