Formulation and Evaluation of Topical Antimicrobial Herbal Cream

Research Article

Abstract

Throughout history, medicinal compounds have been sourced from plants, playing a crucial role in treating various ailments in humans and animals. Presently, a significant portion of hydrogels, pivotal in pharmaceutical drug development, utilize natural ingredients rather than synthetic ones. The Punica granatum L. plant's fruits have been extensively studied for their diverse medicinal advantages, encompassing wound healing, antifungal, anti-inflammatory, and antibacterial properties. Combining herbal extracts may enhance therapeutic effects compared to individual extracts. This study aims to formulate and evaluate a topical herbal cream with antibacterial, anti-inflammatory, and wound-healing attributes against microorganisms. Various parameters such as organoleptic properties, loss on drying, pH, diffusion study, stability study, spreadability, viscosity, consistency, and homogeneity are scrutinized for the herbal cream. The practical application of the prepared herbal cream will be further investigated in vivo.