Development and Evaluation of Novel Topical Polyherbal Cream Containing Aloe vera, Carica papaya and Curcuma longa

Research Article

Abstract

The focus of the present study lies in the development of a versatile herbal cream aimed at moisturizing, nourishing, enhancing skin radiance, and addressing various dermatological conditions. A combination of botanicals, including Aloe babadensis (Aloe vera leaves), Curcuma longa (Turmeric), and Carica papaya (Papaya), was employed for formulation. Four distinct formulations (F1, F2, F3, and F4) were created, each maintaining consistent cream base concentrations while varying concentrations of Aloe vera, Curcuma longa, and Carica papaya extracts. The cream base's oil phase comprised liquid paraffin, coconut oil, and stearic acid, while the aqueous phase included Triethanolamine and glycerine. Other essential components encompassed citric acid, methylparaben, and water (q.s). Aloe vera gel concentrations ranged from 2.0 ml to 8.0 ml, Curcuma longa extract concentrations varied from 0.1 g to 0.4 g, and Carica papaya extract concentrations ranged from 0.2 g to 0.8 g across formulations. Standard characterization methods, including homogeneity, smear type, pH testing, acid value testing, and spreadability testing, were employed. Stability assessments were conducted at 40°C, below 5°C, and at room temperature. All formulations exhibited easy washability, non-irritating properties, and homogeneity. The pH values ranged from 7.3 to 7.6, within the safe range for human skin. Spreadability fell within the range of 6-9, and acid values were 5.6, 5.6, 6.4, and 7.2 for F1, F2, F3, and F4, respectively. The cost-effective herbal cream, composed of a limited number of compounds, demonstrated superiority for skin applications compared to synthetic alternatives, with notable efficiency influenced by Aloe vera gel concentrations