Enhancing pain relief and minimizing infection risk in abdominal surgery: An in-depth comparative investigation

Research Article

Authors

  • Bhargavi Garaga Intern of Pharm. D at Aditya Pharmacy College, Surampalem, Andhra Pradesh, India Author
  • Haritha Kandavalli Intern of Pharm. D at Aditya Pharmacy College, Surampalem, Andhra Pradesh, India Author
  • Hemalatha Yarra Intern of Pharm. D at Aditya Pharmacy College, Surampalem, Andhra Pradesh, India Author
  • Minisha Nalli Intern of Pharm. D at Aditya Pharmacy College, Surampalem, Andhra Pradesh, India Author
  • Rupa Lavanya Gogulamanda Intern of Pharm. D at Aditya Pharmacy College, Surampalem, Andhra Pradesh, India Author
  • Ratna Kumari Padamati Associate Professor in Dept. of Pharmacy Practice at Aditya Pharmacy College, Surampalem, Andhra Pradesh, India Author
  • Dr. Surendra Nath Borra Laparoscopic Surgeon at Trust Multispecialty Hospitals, Kakinada, Andhra Pradesh, India Author

Keywords:

Analgesics, Antibiotics, Post-Operative Pain, Surgical Site Infection, Hernia, Cholelithiasis

Abstract

Analgesics and antibiotics are essential for post-operative treatment because an analgesic typically reduces pain after surgery. By using the right antibiotics, surgical site infections (SSI) can be avoided. The purpose of this study is to assess the effectiveness of analgesics and antibiotics in post-operative hernia and cholelithiasis patients in relation to post-operative pain in surgical site infections. This is a prospective observational study and it is conducted for 6month period between November 2022 to April 2023 in surgical ward at Trust Multispecialty Hospitals, Kakinada, Andhra Pradesh. In this study a total of 115 postoperative subjects were selected, hernias are about 75 subjects and cholelithiasis are 40 subjects. Our study results conducted that, preoperative anesthetics and post-operative analgesics helps the subjects to experience moderate pain after surgery. Weak Opioid (Tramadol), narcotic analgesics (Fentanyl), NSAIDs (Aceclofenac), Paracetamol is given for pain relief. Among 115 subjects were treated with prophylactic antibiotics and none of them had developed with surgical site infection. For prophylaxis of SSI Cephalosporins were preferred as antibiotics like Ceftriaxone, Meropenem, Cefotaxim, (Cefoperazone-Sulbactam), (Piperacillin-Tazobactam) respectively. The study reported the concomitant strict usage of Antibiotics have reduced the incidence of Surgical site infections and the pain perception was reported to be low because of combination of Analgesics rather than the Single dosing and the administration of General Anesthesia before the surgery, along with the surgeon skill

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Published

01-12-2023

How to Cite

Enhancing pain relief and minimizing infection risk in abdominal surgery: An in-depth comparative investigation: Research Article. (2023). Journal of Pharma Insights and Research, 1(2), 134–139. https://jopir.in/index.php/journals/article/view/48