An Exploratory analysis of determinants influencing the quality of life in individuals diagnosed with Pulmonary Arterial Hypertension

Research Article

Abstract

Pulmonary arterial hypertension (PAH) is a rare condition characterized by elevated blood pressure in pulmonary arteries, with an incidence of 15-50 cases per million annually. Improving QOL and increasing survival are the two main objectives of PAH treatment. So to understand and address the multi factors that affect the QOL for providing the holistic patient centric care approach to improve the QOL. A cross-sectional observational study was conducted with in a span of 6-month, chi-square test & regression analysis were employed to examine the association. Patient information was gathered directly from the case sheet additionally physical examination like Blood pressure, SPO2, RR were individually taken. The St. George's Respiratory Questionnaire (SGRQ), Kuppuswamy scale, Morisky medication adherence scale was employed to understand the association between those factors. Our study explores the several factors affecting QOL of PAH patient. Our observation shows that majority of the patient at the age from 61 to 80 and >80 is having low QOL (p<0.001). A significant difference was found between SGRQ and overweight (p=0.03) and also smoking history, low socioeconomic status and poor adherence of drug had negative impact of QOL on both chi square and regression analysis. Our study shows that there is profound and severe influence on the QOL of individual grappling with PAH. The complex interaction between those factors contributes on understanding the challenges face by PAH patient reflect the urgent need of comprehensive care strategies. This study supports our hypothesis that demographic, socioeconomic, clinical factor impact the QOL on PAH patient.