Current Advances in Pharmaceutical Tablet Coating

Review Article

Abstract

Tablet coating is a crucial pharmaceutical process that enhances product functionality, stability, and patient acceptance. Modern coating methods have evolved from simple sugar coating to sophisticated functional film coating systems that enable controlled drug release, taste masking, and enhanced stability. The combination of novel polymeric materials, automated process controls, and advanced coating equipment has revolutionized coating efficiency and reproducibility. Film coating dominates pharmaceutical manufacturing due to its versatility, process efficiency, and ability to achieve specialized functions like enteric protection and modified release profiles. Recent developments include aqueous-based coating systems, specialized polymers for targeted delivery, and novel coating techniques such as ultrasonic spray coating and electrostatic deposition. The advent of "smart" coating systems incorporating stimuli-responsive polymers enables site-specific drug release based on environmental triggers like pH, temperature, or enzymatic activity. Quality by Design (QbD) approaches in coating processes have improved product consistency while reducing manufacturing time and material waste. Continuous coating technologies and real-time process monitoring systems are significant advances in coating efficiency and quality assurance. The combination of innovative coating materials, precise process control, and advanced application techniques has opened new possibilities for tablet coating in pharmaceutical development