A Review on Integration and Evolution of Translational Science in Nigerian Pharmacy Practice

Review Article

Abstract

Translational science is a bridge between laboratory science and clinical applications, with pharmacists playing an increasingly vital role in this process. This review discusses the evolving translational science within Nigerian pharmacy practice, highlighting significant developments, challenges, and future directions. A comprehensive literature assessment was conducted using major scientific databases including PubMed, Scopus, Web of Science, and African Journals Online, covering publications from 2000 to 2024. The search included areas of drug discovery, clinical trials, implementation science, and pharmacovigilance within Nigerian pharmacy practice. Nigerian pharmacists have established significant research programs in natural product development, with over 200 indigenous plants being systematically investigated for therapeutic potential. Their involvement in clinical trials has grown by 45% since 2015, particularly in areas of infectious diseases and chronic conditions. Implementation science initiatives led by pharmacists have resulted in improved medication adherence rates (increase of 3040%) and better chronic disease management outcomes. Significant achievements include the development of pharmacogenomic databases specific to Nigerian populations and the establishment of robust pharmacovigilance networks covering 70% of healthcare facilities. Despite infrastructural and funding limitations, Nigerian pharmacists have made substantial progress in translational science. Significant areas for future development include precision medicine, artificial intelligence applications in drug discovery, and enhanced roles in clinical trial design and management