A Prospective Study of Deep Vein Thrombosis Prophylaxis and Management in ICU Patients

Research Article

Authors

  • Dr. Ravi Prakash Degala Associate Professor and Head of the Department, Department of Pharmacy Practice, Koringa College of Pharmacy, Korangi, Kakinada, Andhra Pradesh, India Author
  • Indu Harini S Assistant Professor, Department of Pharmacy Practice, Koringa College of Pharmacy, Korangi, Kakinada, Andhra Pradesh, India Author
  • Dr. Govinda Rao Kamala Vice-Principal and Professor, Department of Pharmaceutical Analysis, Koringa College of Pharmacy, Korangi, Kakinada, Andhra Pradesh, India Author
  • Dr. Suvarna Jyothi N Principal and Associate Professor, Department of Pharmacology, Koringa College of Pharmacy, Korangi, Kakinada, Andhra Pradesh, India Author
  • Krishnaveni Vydani Associate Professor, Department of Pharmaceutics, Koringa College of Pharmacy, Korangi, Kakinada, Andhra Pradesh, India Author
  • Ratna Priya G Assistant Professor, Department of Pharmacy Practice, Koringa College of Pharmacy, Korangi, Kakinada, Andhra Pradesh, India Author

DOI:

https://doi.org/10.69613/3sw7tq98

Keywords:

Deep Vein Thrombosis, Prophylaxis, Low Molecular Weight Heparin, Thromboprophylaxis

Abstract

A prospective observational study was conducted to evaluate the prophylactic management of Deep Vein Thrombosis (DVT) in 60 patients admitted to the Intensive Care Unit of a tertiary care hospital. The study population included patients with diverse clinical conditions including orthopedic surgeries, cerebrovascular accidents, respiratory conditions, and post-operative cases. The mean age of patients was 59.8 years, with a gender distribution of 48.3% males and 51.7% females. Low Molecular Weight Heparin (LMWH), primarily Clexane (enoxaparin), was the most frequently prescribed prophylactic agent (68.3%), followed by Dabigatrol (20%), and unfractionated Heparin (5%). The standard dosing pattern observed was 0.4ml for Clexane and 220mg for Dabigatrol. The duration of prophylaxis ranged from 1 to 10 days, with an average duration of 5.4 days. Total knee replacement patients consistently received prophylaxis for 6 days. No adverse effects were reported during the study period, and no cases of DVT were documented. This study showed consistent prophylaxis patterns for specific conditions, particularly in orthopedic cases

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Published

05-12-2024

How to Cite

A Prospective Study of Deep Vein Thrombosis Prophylaxis and Management in ICU Patients: Research Article. (2024). Journal of Pharma Insights and Research, 2(6), 158-164. https://doi.org/10.69613/3sw7tq98