A Review on Various Novel Analytical Methods Reported on Favipiravir Estimation
Review Article
Keywords:
Favipiravir, Quantification, Validation, RP-HPLC, HPTLC, COVID-19Abstract
The ongoing and interdependent tasks associated with research and development, quality control, and quality assurance encompass the generation and validation of analytical methods. These methods play a crucial role in risk management and equivalency assessments, aiding in the formulation of product-specific acceptability standards and ensuring consistent outcomes. Validation processes determine the appropriateness of analytical methods for their intended purposes. A comprehensive literature review reveals that Favipiravir can be analyzed individually or in combination with other medications using analytical techniques such as UV spectroscopy, RP-HPLC, and HPTLC. The parameters, including accuracy, precision, robustness, and other aspects of analytical validation, were scrutinized in line with ICH guidelines. The identified techniques are applicable to both bulk and tablet dosage forms of Favipiravir, given their straightforward, sensitive, and reproducible nature. The review also elucidates the applicability and limitations of various published analytical techniques for Favipiravir analysis. Researchers engaged in Favipiravir studies stand to gain significant insights from this comprehensive review
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